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血清抗苗勒管激素在預(yù)測圍絕經(jīng)期女性卵巢功能中的應(yīng)用

發(fā)布時(shí)間:2018-06-24 來源: 美文摘抄 點(diǎn)擊:


  [摘要] 目的 探討血清抗苗勒管激素在預(yù)測圍絕經(jīng)期女性卵巢功能中的應(yīng)用。方法 方便選取該院2016年1月—2017年8月收治的350例圍絕經(jīng)期月經(jīng)失調(diào)女性(即為觀察組)以及同期進(jìn)行常規(guī)體檢的圍絕經(jīng)期120名月經(jīng)正常女性(即為對照組),所有該次實(shí)驗(yàn)參與者先給予常規(guī)婦科生化檢查,而后給予血清抗苗勒管激素,觀察血清抗苗勒管激素檢測對圍絕經(jīng)期女性卵巢功能檢測結(jié)果的影響。結(jié)果 觀察組350例圍絕經(jīng)期月經(jīng)失調(diào)女性均出現(xiàn)不同程度卵巢早衰,聯(lián)合血清抗苗勒管激素檢測前卵巢早衰檢出率為45.4%,聯(lián)合血清抗苗勒管激素檢測后檢出率為86.9%,觀察組圍絕經(jīng)期月經(jīng)失調(diào)卵巢早衰個(gè)體血清抗苗勒管激素明顯低于對照組月經(jīng)正常女性,差異有統(tǒng)計(jì)學(xué)意義(P<0.O5)。結(jié)論 對于圍絕經(jīng)期月經(jīng)失調(diào)女性在常規(guī)婦科生化檢查的基礎(chǔ)上給予血清抗苗勒管激素檢測可有效提高個(gè)體卵巢功能預(yù)測能力。
  [關(guān)鍵詞] 血清抗苗勒管激素;預(yù)測;圍絕經(jīng)期女性;卵巢功能
  [中圖分類號] R711 [文獻(xiàn)標(biāo)識碼] A [文章編號] 1674-0742(2018)01(c)-0094-03
  [Abstract] Objective This paper tries to observe the application of serum anti-Mullerian hormone in predicting the ovarian function of perimenopausal women. Methods From January 2016 to August 2017,350 cases of perimenopausal menopausal women(as the observation group) and 120 cases of menopausal menopausal women who had regular physical examination were convenient treated with normal menstrual period(as the control group). All the participants in this experiment should be given routine biochemical examination of gynecological gynecology, and then given serum anti-Mullerian hormone, observe the serum anti-Muller tube hormone detection of perimenopausal women ovarian function test results. Results The incidence rate of premature ovarian premature rupture was 45.4% in patients with premature menopausal menstrual disorders who had different levels of ovarian premature rupture and combined with serum anti-Mullerian hormone test. The detection rate of serum anti-Mullerian hormone was 86.9%, the observation group perimenopausal menstrual disorders ovarian premature aging individual anti-Mullerian hormone was significantly lower than the control group of menstrual normal women, with statistical significance(P<0.05). Conclusion Serum anti-Mullerian hormone test can be used to improve the prediction ability of ovarian function in patients with perimenopausal menopausal women under routine gynecological biochemical tests.
  [Key words] Serum anti-Mullerian hormone; Prediction; Perimenopausal women; Ovarian function
  一般而言,女性30歲后卵巢功能可出現(xiàn)不同程度的衰退,由于個(gè)體差異的影響,女性卵巢功能衰退的速度不同,對女性卵巢功能進(jìn)行準(zhǔn)確預(yù)測可提高臨床干預(yù)效果[1-3]。目前臨床常用婦科生化檢查包括血清卵泡刺激素(FSH)、黃體生成素(LH)、雌二醇(E2)等從而對個(gè)體卵巢功能進(jìn)行預(yù)測。近些年臨床研究認(rèn)為FSH、LH以及E2的分泌受到下丘腦、垂體反饋調(diào)控的影響,可增加卵巢功能測定的不準(zhǔn)確性,因此如何采取積極準(zhǔn)確的激素測量從而提高圍絕經(jīng)期女性卵巢功能判定就顯得十分重要[4]。該次實(shí)驗(yàn)對該院2016年1月—2017年8月收治的350例圍絕經(jīng)期月經(jīng)失調(diào)女性以及同期進(jìn)行常規(guī)體檢的圍絕經(jīng)期120名月經(jīng)正常女性為該次實(shí)驗(yàn)研究對象,觀察組350例圍絕經(jīng)期月經(jīng)失調(diào)女性聯(lián)合血清抗苗勒管激素檢測前后個(gè)體卵巢早衰檢出情況以及觀察組與對照組女性實(shí)驗(yàn)室檢測結(jié)果,從而論證血清抗苗勒管激素對圍絕經(jīng)期女性卵巢功能預(yù)測應(yīng)用價(jià)值。
  1 資料與方法
  1.1 一般資料
  觀察組為方便選取該院收治的350例圍絕經(jīng)期月經(jīng)失調(diào)女性,所有女性均出現(xiàn)月經(jīng)周期紊亂、經(jīng)期長短不一、經(jīng)量不定、月經(jīng)稀發(fā)甚至閉經(jīng)等月經(jīng)失調(diào)現(xiàn)象,患者年齡在40~55歲,平均年齡在(38.9±1.1)歲,患者月經(jīng)失調(diào)持續(xù)時(shí)間最短為4個(gè)月,持續(xù)時(shí)間最長為3年,患者平均病程在(5.9±1.2)個(gè)月。對照組為同期進(jìn)行常規(guī)體檢的絕經(jīng)期正常女性,年齡在40~55歲,平均年齡在(38.9±1.1)歲。該次實(shí)驗(yàn)圍絕經(jīng)期月經(jīng)失調(diào)女性患者與圍絕經(jīng)期月經(jīng)正常女性在年齡等一般資料上差異無統(tǒng)計(jì)學(xué)意義(P>0.05)。

相關(guān)熱詞搜索:絕經(jīng)期 血清 激素 預(yù)測 女性

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