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降鈣素聯合臭氧、透明質酸鈉對膝關節(jié)炎患者Lequesne評分及關節(jié)指數積分的影響

發(fā)布時間:2018-06-24 來源: 感悟愛情 點擊:


  [摘要] 目的 探討降鈣素聯合臭氧、透明質酸鈉對膝骨關節(jié)炎患者Lequesne評分及關節(jié)指數積分的影響,為膝關節(jié)炎患者臨床治療提供理論參考。方法 方便選擇2015年1月—2017年7月該院收治的膝關節(jié)炎患者200例,隨機分為兩組,每組100例;在常規(guī)治療的基礎上,對照組患者采用臭氧、透明質酸鈉治療,觀察組患者在對照組的基礎上加用降鈣素治療;采用膝骨性關節(jié)炎嚴重性指數(Lequesne)比較兩組患者膝關節(jié)炎治療情況,根據治療后患者關節(jié)指數積分進步情況對評價臨床療效。結果 治療后,兩組患者Lequesne評分均降低,且觀察組(6.37±1.33)分低于對照組(8.89±1.38)分;觀察組治療總有效率(96.0%)明顯高于對照組(81.0%),差異有統計學意義(P<0.05)。結論 降鈣素聯合醫(yī)用臭氧、透明質酸鈉能夠有效降低膝關節(jié)炎患者Lequesne評分,療效確切,臨床推廣價值高。
  [關鍵詞] 降鈣素;臭氧;透明質酸鈉;Lequesne評分;臨床療效
  [中圖分類號] R684 [文獻標識碼] A [文章編號] 1674-0742(2018)01(c)-0015-03
  [Abstract] Objective This paper tries to investigate the effects of calcitonin combined with ozone and sodium hyaluronate on Lequesne score and joint index score in patients with knee osteoarthritis, and to provide theoretical reference for the clinical treatment of patients with knee osteoarthritis. Methods 200 cases of patients with knee osteoarthritis from January 2015 to July 2017 in this hospital were conveient selected, and were randomly divided into two groups, with 100 patients each group; On the basis of conventional treatment, the control group was given ozone and sodium hyaluronate for treatment, and the observation group was treated with calcitonin on the basis of control group; The knee osteoarthritis severity index (Lequesne) was compared for the treatment of knee arthritis in two groups, according to the progress of the patients’ joint index scores, the clinical efficacy was evaluated. Results After treatment, Lequesne scores decreased in both groups, and the scores of observation group (6.37±1.33) points was lower than control group (8.89±1.38) points, the total effective rate of observation group(96.0%) was significantly higher than control group (81.0%), the difference was statistically significant(P<0.05). Conclusion Calcitonin combined with medical ozone and sodium hyaluronate can effectively reduce the Lequesne score in patients with knee osteoarthritis, the curative effect is exact, the clinical popularization value is high.
  [Key words] Calcitonin; Ozone; Sodium hyaluronate; Lequesne score; Clinical efficacy
  膝關節(jié)炎是指膝骨性關節(jié)炎,是一種以退行性病理改變(包含關節(jié)軟骨代謝紊亂和降解等)為基礎的慢性關節(jié)炎性疾病,在中老年群體中發(fā)病率較高,60歲以上人群的發(fā)病率高達42.8%,在75歲人群中發(fā)病率高達80.0%,是造成患者肢體殘疾的重要病因之一[1]。隨著我國人口老齡化的加重,世界衛(wèi)生組織預測我國將成為膝關節(jié)炎數量最多的國家之一,且由于膝關節(jié)炎致殘率較高,會使患者失去勞動能力,對患者正常生活造成負擔,因此,膝關節(jié)炎的治療十分重要[2]。膝關節(jié)炎致病原因多,在臨床治療上存在較大阻礙,目前臨床上以非藥物保守治療及手術治療為主,以求達到消炎、緩解關節(jié)疼痛的作用。該研究探討該院2015年1月—2017年7月期間100例服用降鈣素聯合臭氧、透明質酸鈉的膝關節(jié)炎患者與100例采用臭氧、透明質酸鈉治療的膝關節(jié)炎患者治療前后膝骨性關節(jié)炎嚴重性指數(Lequesne)評分及關節(jié)指數積分的比較,現報道如下。
  1 資料與方法

相關熱詞搜索:膝關節(jié) 臭氧 關節(jié) 患者 評分

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