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實(shí)驗(yàn)室指標(biāo)對(duì)多發(fā)性骨髓瘤的診斷價(jià)值分析

發(fā)布時(shí)間:2018-06-23 來源: 感悟愛情 點(diǎn)擊:

http://img1.qikan.com.cn/qkimages/yxxi/yxxi201805/yxxi20180556-1-l.jpghttp://img1.qikan.com.cn/qkimages/yxxi/yxxi201805/yxxi20180556-2-l.jpg
  摘   要:目的  分析多發(fā)性骨髓瘤實(shí)驗(yàn)室結(jié)果對(duì)多發(fā)性骨髓瘤的診斷價(jià)值。方法  以2015年1月~2017年5月我院收治和確診的28例的多發(fā)性骨髓瘤患者作為研究對(duì)象,回顧分析其室驗(yàn)室指標(biāo)的特性,包括HBG、UA、Scr、TP、GLO、A/G、ESR、B-J、β2-MG、尿蛋白定性、IgG、IgA、IgM。結(jié)果  28例MM患者中,有26例(92.86%)HBG<90 g/L,25例(89.28%)UA、Scr升高,22例(78.57%)TP升高、22例(78.57%)GLO升高,25例(89.28%)A/G倒置,28例(100.00%)MM患者ESR明顯升高,14例(50.00%)B-J陽性,26例(92.86%)尿蛋白定性陽性,26例(92.86%)β2-MG升高,19例(67.86%)IgG明顯升高,6例(21.43%)IgA明顯升高。結(jié)論  HBG、UA、Scr、TP、GLO、A/G、ESR、IgG、IgA等實(shí)驗(yàn)室結(jié)果對(duì)臨床診斷MM有一定的靈敏度和特異性,臨床檢驗(yàn)人員應(yīng)引起重視,加強(qiáng)與臨床溝通,做到早診斷、早治療,防止誤診、漏診。
  關(guān)鍵詞:多發(fā)性骨髓瘤;實(shí)驗(yàn)室結(jié)果;診斷價(jià)值
  中圖分類號(hào):R446.1;R733.3                            文獻(xiàn)標(biāo)識(shí)碼:A                           DOI:10.3969/j.issn.1006-1959.2018.05.056
  文章編號(hào):1006-1959(2018)05-0155-03
  Diagnostic Value of Laboratory Markers for Multiple Myeloma
  HUANG Zhen-yan
  (Department of Laboratory,Wuming Hospital Affiliated to Guangxi Medical University,Wuming 530199,Guangxi,China)
  Abstract:Objective  To analyze the diagnostic value of multiple myeloma laboratory results for multiple myeloma.Methods  In January 2015~2017 year in May in our hospital and diagnosed 28 cases of multiple myeloma patients as the research object,analyzed its characteristics of room laboratory indexes,including HBG,UA,Scr,TP,GLO,A/G,ESR,B-J,2-MG,β2-MG,qualitative urine protein, IgG,IgA,IgM.Results  Among 28 cases of MM,26 cases(92.86%)HBG<90g/L,25 cases(89.28%)increased UA and Scr,22 cases(78.57%) increased TP,22 cases(78.57%)GLO increased,25 cases(89.28%)AG reversed.The ESR of 28 patients with MM(100.00%)was significantly higher,14 patients(50.00%)were positive for B-J,26 patients(92.86%)were positive for urinary protein,26 patients(92.86%)were elevated for β2-MG,and 19 patients(67.86%)IgG was significantly elevated,and IgA in 6 patients(21.43%)was significantly higher.Conclusion  The laboratory results of HBG,UA,Scr,TP,GLO,A/G,ESR,IgG and IgA have certain sensitivity and specificity for clinical diagnosis of MM.The clinical laboratory staff should pay attention to it,strengthen communication with clinic,make early diagnosis and early treatment,so as to prevent misdiagnosis and missed diagnosis.
  Key words:Multiple myeloma;Laboratory results;Diagnostic value
  多發(fā)性骨髓瘤(multiple my eloma,MM)是發(fā)生在人體骨髓的多灶性漿細(xì)胞異常增生的惡性腫瘤,是惡性漿細(xì)胞疾病中最為常見的一種。MM起病隱匿,臨床表現(xiàn)復(fù)雜多樣,且無明顯特異性,易導(dǎo)致誤診、漏診。主要表現(xiàn)在血液、骨胳、腎臟等方面的損傷,易診斷為血液、骨科、腎臟疾病,造成誤診[1-2]。為了進(jìn)一步促進(jìn)早發(fā)現(xiàn)、早診斷、早治療MM,現(xiàn)以2015年1月~2017年5月我院收治和確診的28例病例作為研究對(duì)象,分析、探討實(shí)驗(yàn)室系列指標(biāo)對(duì)此類疾病的臨床診斷價(jià)值。

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